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Top3α is the replicative topoisomerase in mitochondrial DNA replication.
Hangas A, Kekäläinen NJ, Potter A, Michell C, Aho KJ, Rutanen C, Spelbrink JN, Pohjoismäki JL, Goffart S. Hangas A, et al. Among authors: pohjoismaki jl. Nucleic Acids Res. 2022 Aug 26;50(15):8733-8748. doi: 10.1093/nar/gkac660. Nucleic Acids Res. 2022. PMID: 35904803 Free PMC article.
TFAM knockdown-triggered mtDNA-nucleoid aggregation and a decrease in mtDNA copy number induce the reorganization of nucleoid populations and mitochondria-associated ER-membrane contacts.
Aasumets K, Basikhina Y, Pohjoismäki JL, Goffart S, Gerhold J. Aasumets K, et al. Among authors: pohjoismaki jl. Biochem Biophys Rep. 2021 Sep 24;28:101142. doi: 10.1016/j.bbrep.2021.101142. eCollection 2021 Dec. Biochem Biophys Rep. 2021. PMID: 34622037 Free PMC article.
Mammalian mitochondrial DNA replication intermediates are essentially duplex but contain extensive tracts of RNA/DNA hybrid.
Pohjoismäki JL, Holmes JB, Wood SR, Yang MY, Yasukawa T, Reyes A, Bailey LJ, Cluett TJ, Goffart S, Willcox S, Rigby RE, Jackson AP, Spelbrink JN, Griffith JD, Crouch RJ, Jacobs HT, Holt IJ. Pohjoismäki JL, et al. J Mol Biol. 2010 Apr 16;397(5):1144-55. doi: 10.1016/j.jmb.2010.02.029. Epub 2010 Feb 23. J Mol Biol. 2010. PMID: 20184890 Free PMC article.
21 results